This study examines the influence of job-related factors—specifically job control, job demand, and social support—on lecturer performance in Hanoi, Vietnam. In the face of rising competition, job performance has become a critical focus for organizations. The performance of individual employees and their collaborative efforts are essential for overall organizational success. This research uses the job demand-control and social support model to analyze the factors affecting the performance of university lecturers in Vietnam. A questionnaire with 153 completed responses was distributed to lecturers in Hanoi through an online platform. Data analysis using AMOS and SPSS confirmed the hypothesis. The findings showed that job demand negatively affects lecturer performance, while both job control and social support positively influence it. Furthermore, the study found that job control and social support moderate the relationship between job demand and lecturer performance. Based on these results, this study offers recommendations for university managers to enhance lecturer performance.