This study aimed to assess the job satisfaction of pharmacists across five different practice settings in Nigeria, focusing on different elements of their work environment. It also assessed how demographic factors such as age, gender, and academic qualifications affect satisfaction levels. The study used a cross-sectional survey design, with a sample size of 618 graduate pharmacists, selected through simple random sampling. Pre-tested questionnaires were used to collect data. The findings showed that the majority of pharmacists, especially those in hospital settings, were dissatisfied with their work environment (χ2 (4) = 9.652, P = .047). Younger pharmacists (χ2 (3) = 17.346, P = .001), unmarried individuals (χ2 (3) = 12.558, P = .006), those with less work experience (χ2 (5) = 47.701, P = .000), lower cadre pharmacists (χ2 (2) = 32.641, P = .000), and those with only a first degree (χ2 (2) = 9.228, P = .010) showed lower job satisfaction. The study found that while overall satisfaction is low among Nigerian pharmacists, there are significant variations based on age, marital status, experience, education, and practice setting, with academic pharmacists being the most satisfied and hospital pharmacists being the least satisfied.
